Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895740 | 0.83 | CYP2A6 (0.64) | CYP2A6MAPTIDO1NPSR1CYP1A2 | |
| SCHEMBL29396424 | 0.83 | CYP2A6 (0.64) | CYP2A6MAPTIDO1NPSR1CYP1A2 | |
| Phosphine SCHEMBL29222824 | 0.82 | CYP2A6 (0.62) | CYP2A6MAPTIDO1NPSR1CYP1A2 | |
| SCHEMBL29222843 | 0.80 | CYP2A6 (0.66) | CYP2A6MAPTIDO1NPSR1CYP1A2 | |
| SCHEMBL3809659 | 0.79 | CYP2A6 (0.64) | CYP2A6MAPTIDO1NPSR1CYP1A2 | |
| SCHEMBL28181946 | 0.79 | CYP2A6 (0.69) | CYP2A6MAPTIDO1NPSR1CYP1A2 | |
| SCHEMBL2458423 | 0.79 | CYP2A6 (0.69) | CYP2A6MAPTIDO1NPSR1CYP1A2 | |
| SCHEMBL2458425 | 0.79 | CYP2A6 (0.69) | CYP2A6MAPTIDO1NPSR1CYP1A2 | |
| Bromomethane SCHEMBL9679512 | 0.78 | CYP2A6 (0.58) | CYP2A6MAPTIDO1NPSR1CYP1A2 | |
| SCHEMBL663629 | 0.77 | CYP2A6 (0.61) | CYP2A6MAPTIDO1NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217764-A1 | NOX INHIBITORS FOR USE IN THE TREATMENT OF ALPORT SYNDROME | CALLIDITAS THERAPEUTICS SUISSE SA (CH) | 2023-11-16 | — | — | WO | claimed |
| US-20210177811-A1 | USE OF NOX INHIBITORS FOR TREATMENT OF CANCER | CALLIDITAS THERAPEUTICS SUISSE SA (CH) | 2021-06-17 | — | — | US | claimed |
| EP-3703747-A1 | USE OF NOX INHIBITORS FOR TREATMENT OF CANCER | GenKyoTex Suisse SA (CH) | 2020-09-09 | — | — | EP | claimed |
| EP-3479843-A1 | USE OF NOX INHIBITORS FOR TREATMENT OF CANCER | GenKyoTex Suisse SA (CH) | 2019-05-08 | — | — | EP | claimed |
| CN-105814027-A | Novel compounds for the regeneration of terminally differentiated cells and tissues | 阿库西亚医疗有限责任公司 | 2016-07-27 | — | — | CN | claimed |
| CN-105283224-A | Composition comprising a combination of an acrylic polymer, a silicone copolymer and an amino acid or amino acid derivative | OREAL | 2016-01-27 | — | — | CN | claimed |
| CN-101356186-A | Prion-specific peptoid reagents | NOVARTIS AG (CH) | 2009-01-28 | — | — | CN | claimed |
| US-20080076762-A1 | Novel 4-Aminopiperidine Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-03-27 | — | — | US | claimed |
| CN-101102775-A | Methods of using PDEV inhibitors for the treatment of congestive heart failure | SCHERING CORP (US) | 2008-01-09 | — | — | CN | claimed |
| CN-101084201-A | Triazolone, tetrazolone and imidazolone derivatives for use as alpha-2c adrenoreceptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2007-12-05 | — | — | CN | claimed |
| EP-0739338-A4 | NOVEL SERINE PROTEASE INHIBITORS: DERIVATIVES OF ISOTHIAZOLIDIN-3-ONE-1,1 DIOXIDE AND 3-OXO-1,2,5-THIADIAZOLIDINE-1,1-DIOXIDE | UNIV WICHITA STATE (US) | 1997-03-26 | — | — | EP | claimed |
| EP-0739338-A1 | NOVEL SERINE PROTEASE INHIBITORS: DERIVATIVES OF ISOTHIAZOLIDIN-3-ONE-1,1 DIOXIDE AND 3-OXO-1,2,5-THIADIAZOLIDINE-1,1-DIOXIDE | THE WICHITA STATE UNIVERSITY (US) | 1996-10-30 | — | — | EP | claimed |
| US-5550139-A | ANTIINFLAMMATORY AGENT, ANTITUMOR AGENT, ANTICARCINOGENIC AGENT | THE WICHITA STATE UNIVERSITY (US) | 1996-08-27 | — | — | US | claimed |
| WO-1995018797-A1 | NOVEL SERINE PROTEASE INHIBITORS: DERIVATIVES OF ISOTHIAZOLIDIN-3-ONE-1,1 DIOXIDE AND 3-OXO-1,2,5-THIADIAZOLIDINE-1,1-DIOXIDE | THE WICHITA STATE UNIVERSITY (US) | 1995-07-13 | — | — | WO | claimed |
| CN-1061411-A | Be used to strengthen the active quinazoline derivant of antineoplastic agent | PFIZER (US) | 1992-05-27 | — | — | CN | claimed |
| CN-1033803-A | The preparation of hypotensive agent mercapto-acylamino acid | SCHERING CORP (US) | 1989-07-12 | — | — | CN | claimed |
| EP-0199379-A2 | Pharmacologically active tripeptides and process for their synthesis | ENIRICERCHE S.p.A. (IT) | 1986-10-29 | — | — | EP | claimed |
| US-4558034-A | Inhibitors of bacterial collagenase | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF KENTUCKY (US) | 1985-12-10 | — | — | US | claimed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | claimed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076762-A1 | Novel 4-Aminopiperidine Derivatives | METAP1, DNPEP, PEPD | CYP2A6 2588/4885MAPT 3156/4885IDO1 186/4885 |
| US-20210177811-A1 | USE OF NOX INHIBITORS FOR TREATMENT OF CANCER | NOX1, NOX5, NOX3 | CYP2A6 4150/4885MAPT 3281/4885IDO1 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.