SCHEMBL1707453

SCHEMBL1707453

NC(=O)CC(=O)CC(=O)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.64
MAPT P10636 3/20 0.64
KMT2A Q03164 3/20 0.64
TDP1 Q9NUW8 3/20 0.64
MEN1 O00255 2/20 0.64
HPGD P15428 2/20 0.64
MAPK1 P28482 2/20 0.64
KDM4E B2RXH2 1/20 0.64
ALOX15 P16050 1/20 0.64
CES1 P23141 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
PTPN1 P18031 2/20 0.55
ERCC5 P28715 2/20 0.55
FEN1 P39748 2/20 0.55
ALDH1A1 P00352 4/20 0.52
CYP2C19 P33261 3/20 0.52
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
HIF1A Q16665 2/20 0.52
PLOD2 O00469 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1200893 0.89 CYP3A4 (0.73) CYP3A4MAPTKMT2ATDP1MEN1
SCHEMBL1977011 0.89 KMT2A (0.80) CYP3A4MAPTKMT2ATDP1MEN1
SCHEMBL10888944 0.87 KMT2A (0.76) CYP3A4MAPTKMT2ATDP1MEN1
SCHEMBL6120813 0.83 KMT2A (0.70) CYP3A4MAPTKMT2ATDP1MEN1
Benzamide SCHEMBL2108537 0.80 CYP3A4 (0.76) CYP3A4MAPTKMT2ATDP1MEN1
Dibenzoylmethane SCHEMBL10356288 0.79 MEN1 (1.00) CYP3A4MAPTKMT2ATDP1MEN1
Dibenzoylmethane SCHEMBL1704711 0.79 MEN1 (1.00) CYP3A4MAPTKMT2ATDP1MEN1
Dibenzoylmethane SCHEMBL39582 0.79 MEN1 (1.00) CYP3A4MAPTKMT2ATDP1MEN1
SCHEMBL3071016 0.79 KMT2A (0.64) CYP3A4MAPTKMT2ATDP1MEN1
SCHEMBL11056976 0.79 KMT2A (0.60) CYP3A4MAPTKMT2ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2169042-B1 Composition comprising microcapsules PROCTER & GAMBLE (US) 2012-04-18 EP claimed
CN-105769590-B Delivery of particles 宝洁公司 2019-10-25 CN disclosed
CN-109642185-A Fabrid care composition comprising glycerol ester copolymer 宝洁公司 2019-04-16 CN disclosed
CN-107849825-A Fabrid care composition comprising metathesized unsaturated polyol ester 宝洁公司 2018-03-27 CN disclosed
CN-107847768-A Method for preparing a composition comprising multiple populations of microcapsules 宝洁公司 2018-03-27 CN disclosed
CN-107835681-A Composition comprising a plurality of populations of microcapsules comprising perfume 宝洁公司 2018-03-23 CN disclosed
WO-2017004343-A1 FEEDSTOCK COMPOSITIONS CONTAINING MULTIPLE POPULATIONS OF MICROCAPSULES AND METHODS FOR MAKING THE PROCTER & GAMBLE COMPANY (US) 2017-01-05 WO disclosed
EP-2866792-A2 MICROPARTICLE FORMULATIONS FOR DELIVERY TO THE LOWER AND CENTRAL RESPIRATORY TRACT AND METHODS OF MANUFACTURE Ansun Biopharma, Inc. (US) 2015-05-06 EP disclosed
WO-2014005103-A2 MICROPARTICLE FORMULATIONS FOR DELIVERY TO THE LOWER AND CENTRAL RESPIRATORY TRACT AND METHODS OF MANUFACTURE ANSUN BIOPHARMA, INC. (US) 2014-01-03 WO disclosed
EP-2094828-A1 BENEFIT AGENT CONTAINING DELIVERY PARTICLE APPLETON PAPERS INC. (US) 2009-09-02 EP disclosed
WO-2008063635-A1 BENEFIT AGENT CONTAINING DELIVERY PARTICLE APPLETON PAPERS INC. (US) 2008-05-29 WO disclosed