SCHEMBL1200893

SCHEMBL1200893

NC(=O)CC(=O)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.73
MAPT P10636 3/20 0.73
TDP1 Q9NUW8 3/20 0.73
KMT2A Q03164 3/20 0.73
MEN1 O00255 2/20 0.73
HPGD P15428 2/20 0.73
MAPK1 P28482 2/20 0.73
KDM4E B2RXH2 1/20 0.73
ALOX15 P16050 1/20 0.73
CES1 P23141 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
PTPN1 P18031 2/20 0.61
ERCC5 P28715 2/20 0.61
FEN1 P39748 2/20 0.61
ALDH1A1 P00352 4/20 0.57
CYP2C19 P33261 3/20 0.57
NPC1 O15118 3/20 0.57
RAB9A P51151 3/20 0.57
HIF1A Q16665 2/20 0.57
PLOD2 O00469 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1707453 0.89 CYP3A4 (0.64) CYP3A4MAPTTDP1KMT2AMEN1
SCHEMBL11056976 0.88 KMT2A (0.60) CYP3A4MAPTTDP1KMT2AMEN1
Dibenzoylmethane SCHEMBL39582 0.85 MEN1 (1.00) CYP3A4MAPTTDP1KMT2AMEN1
Dibenzoylmethane SCHEMBL10356288 0.85 MEN1 (1.00) CYP3A4MAPTTDP1KMT2AMEN1
Dibenzoylmethane SCHEMBL1704711 0.85 MEN1 (1.00) CYP3A4MAPTTDP1KMT2AMEN1
SCHEMBL8599336 0.84 CYP3A4 (0.70) CYP3A4MAPTTDP1KMT2AMEN1
SCHEMBL10789236 0.84 TSHR (0.55) CYP3A4MAPTTDP1KMT2AMEN1
SCHEMBL24209329 0.82 ERCC5 (0.70) CYP3A4MAPTTDP1KMT2AMEN1
Dibenzoylmethane SCHEMBL6598370 0.82 MEN1 (0.94) CYP3A4MAPTTDP1KMT2AMEN1
Dibenzoylmethane SCHEMBL21597905 0.82 MEN1 (0.94) CYP3A4MAPTTDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823012-A Carbodiimide modified TDI catalyst, preparation method and application thereof 万华化学集团股份有限公司 2025-04-15 CN claimed
CN-114432160-A Dental composite material, multilayer dental composite material, and preparation method and application thereof 香港城市大学深圳研究院 2022-05-06 CN claimed
CN-106397163-A Method for removal of methanamide by dichlorination 重庆大学 2017-02-15 CN claimed
US-20150299143-A1 SUBSTITUTED TRIAZOLE AND IMIDAZOLE COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2015-10-22 US claimed
EP-1971600-B1 ISOXAZOLE DERIVATIVES AND USE THEREOF SK BIOPHARMACEUTICALS CO LTD (KR) 2013-08-21 EP claimed
CN-103059215-A Glycine betaine ester intelligent hydrogel relatively controllable in structure and preparation method and application UNIV SOUTH CHINA TECH 2013-04-24 CN claimed
US-7705064-B2 Photosensitive compounds, photopolymerizable compositions including the same, and methods of making and using the same HENKEL CORPORATION (US) 2010-04-27 US claimed
US-20090131336-A1 Isoxazole Derivatives and Use Thereof SK BIOPHARMACEUTICALS CO., LTD. (KR) 2009-05-21 US claimed
US-20090030106-A1 Photosensitive Compounds, Photopolymerizable Compositions Including the Same, and Methods of Making and Using the Same HENKEL CORPORATION (US) 2009-01-29 US claimed
WO-2009014689-A2 PHOTOSENSITIVE COMPOUNDS, PHOTOPOLYMERIZABLE COMPOSITIONS INCLUDING THE SAME, AND METHODS OF MAKING AND USING THE SAME HENKEL CORPORATION (US) 2009-01-29 WO claimed
EP-1971600-A1 ISOXAZOLE DERIVATIVES AND USE THEREOF SK Holdings Co., Ltd. (KR) 2008-09-24 EP claimed
WO-2007078113-A1 ISOXAZOLE DERIVATIVES AND USE THEREOF SK HOLDINGS CO., LTD. (KR) 2007-07-12 WO claimed
WO-1998022822-A9 PHOTOGRAPHIC COLOR COUPLERS USED AS CYTOCHEMICAL CONTRAST MARKERS 1998-09-11 WO claimed
WO-1998022822-A1 PHOTOGRAPHIC COLOR COUPLERS USED AS CYTOCHEMICAL CONTRAST MARKERS APPLIED IMAGING CORPORATION (US) 1998-05-28 WO claimed
US-4842979-A WITH A DIAZONIUM SALT, 2-HYDROXY-3-NAPHTHOIC ANILIDE, 2-HYDROXY-3-NAPHTHOIC AMIDE FUJI PHOTO FILM CO., LTD. (JP) 1989-06-27 US claimed
EP-0312657-A1 Colour photographic elements incorporating alkali-labile couplers AGFA-GEVAERT N.V. (BE) 1989-04-26 EP claimed
EP-0009702-B1 A PHENYLALKYLAMINOETHYLSALICYLAMIDE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT SCHERING CORPORATION (US) 1981-11-04 EP claimed
JP-59142182-A None JP disclosed
US-3932182-A An organic photoconductive composition comprising an organic photoconductive compound and a sensitizing compound having an active methylene group MITSUBISHI PAPER MILLS, LTD. (JA) 1976-01-13 US disclosed
US-3930866-A MAGENTA FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030106-A1 Photosensitive Compounds, Photopolymerizable Compositions Including the Same, and Methods of Making and Using the Same PHYKPL, AHCY, ALAD CYP3A4 1075/4885MAPT 4110/4885TDP1 1082/4885
US-20150299143-A1 SUBSTITUTED TRIAZOLE AND IMIDAZOLE COMPOUNDS HDAC7, PSMB7, IKZF3 CYP3A4 899/4885MAPT 3483/4885TDP1 1665/4885
US-20090131336-A1 Isoxazole Derivatives and Use Thereof WNT3A, WNT1, WNT3 CYP3A4 192/4885MAPT 2497/4885TDP1 4243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.