Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 19/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17074671 | 1.00 | ADRB2 (0.70) | ADRB2ADRB1 | |
| SCHEMBL17074664 | 0.99 | ADRB2 (0.72) | ADRB2ADRB1 | |
| SCHEMBL17074663 | 0.99 | ADRB2 (0.72) | ADRB2ADRB1 | |
| SCHEMBL17074677 | 0.85 | ADRB2 (0.76) | ADRB2ADRB1 | |
| SCHEMBL19984602 | 0.85 | ADRB2 (0.76) | ADRB2ADRB1 | |
| SCHEMBL17074678 | 0.85 | ADRB2 (0.76) | ADRB2ADRB1 | |
| SCHEMBL17074700 | 0.85 | ADRB2 (0.79) | ADRB2ADRB1 | |
| SCHEMBL17074699 | 0.85 | ADRB2 (0.79) | ADRB2ADRB1 | |
| SCHEMBL27950321 | 0.85 | ADRB2 (0.79) | ADRB2ADRB1 | |
| SCHEMBL17074621 | 0.84 | ADRB2 (0.81) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718280-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMA SPA (IT) | 2015-09-16 | — | — | EP | claimed |