Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707590 | 1.00 | TBXAS1 (0.38) | TBXAS1SIRT6NAPRTTDP1KDM4E | |
| SCHEMBL1913983 | 0.81 | TBXAS1 (0.38) | TBXAS1KDM4EL3MBTL1 | |
| SCHEMBL1706868 | 0.78 | AKR1C3 (0.40) | TBXAS1SIRT6NAPRTALDH1A1 | |
| SCHEMBL1706870 | 0.78 | AKR1C3 (0.40) | TBXAS1SIRT6NAPRTALDH1A1 | |
| SCHEMBL12499645 | 0.77 | TBXAS1 (0.50) | TBXAS1NAPRTL3MBTL1ALDH1A1 | |
| SCHEMBL12499649 | 0.77 | TBXAS1 (0.50) | TBXAS1NAPRTL3MBTL1ALDH1A1 | |
| SCHEMBL1914012 | 0.75 | TBXAS1 (0.47) | TBXAS1TDP1 | |
| SCHEMBL1914188 | 0.74 | TBXAS1 (0.38) | TBXAS1ALDH1A1 | |
| SCHEMBL1969309 | 0.73 | KDM4E (0.41) | TBXAS1KDM4EL3MBTL1 | |
| SCHEMBL16737458 | 0.73 | KDM4E (0.42) | TBXAS1KDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | disclosed |