Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707637 | 1.00 | ROCK2 (0.41) | ROCK2CCR2ROCK1L3MBTL1HDAC1 | |
| Hydrochloric Acid SCHEMBL1707329 | 0.99 | ROCK2 (0.40) | ROCK2CCR2ROCK1L3MBTL1HDAC1 | |
| Hydrochloric Acid SCHEMBL1707276 | 0.99 | ROCK2 (0.40) | ROCK2CCR2ROCK1L3MBTL1HDAC1 | |
| Hydrochloric Acid SCHEMBL1707327 | 0.99 | ROCK2 (0.40) | ROCK2CCR2ROCK1L3MBTL1HDAC1 | |
| SCHEMBL1708505 | 0.95 | HDAC1 (0.39) | ROCK2CCR2ROCK1L3MBTL1HDAC1 | |
| SCHEMBL1708503 | 0.95 | HDAC1 (0.39) | ROCK2CCR2ROCK1L3MBTL1HDAC1 | |
| Hydrochloric Acid SCHEMBL1706849 | 0.94 | HDAC1 (0.38) | ROCK2CCR2ROCK1L3MBTL1HDAC1 | |
| Hydrochloric Acid SCHEMBL1707417 | 0.94 | HDAC1 (0.38) | ROCK2CCR2ROCK1L3MBTL1HDAC1 | |
| Hydrochloric Acid SCHEMBL1706853 | 0.94 | HDAC1 (0.38) | ROCK2CCR2ROCK1L3MBTL1HDAC1 | |
| SCHEMBL1708431 | 0.92 | ROCK2 (0.42) | ROCK2CCR2ROCK1CCR3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | claimed |
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | disclosed |