Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | KRAS | P01116 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17063344 | 0.84 | SMN1; SMN2 (0.47) | ACHEF2 | |
| SCHEMBL17063383 | 0.83 | KDM4E (0.46) | ACHEF2 | |
| SCHEMBL17063266 | 0.80 | POLB (0.50) | ACHEF2 | |
| SCHEMBL17063253 | 0.79 | FPR2 (0.48) | KRAS | |
| SCHEMBL1581511 | 0.79 | KMT2A (0.53) | — | |
| SCHEMBL17063326 | 0.79 | SMN1; SMN2 (0.51) | F2 | |
| SCHEMBL17063250 | 0.75 | SMN1; SMN2 (0.47) | F2 | |
| SCHEMBL17458530 | 0.75 | CHRM1 (0.48) | HTR7FABP4 | |
| SCHEMBL17063357 | 0.74 | HTR2A (0.47) | HTR7KRASNTSR1 | |
| Hydrochloric Acid SCHEMBL17063302 | 0.73 | HTR2A (0.46) | HTR7KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116504-A2 | RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | Innov17 LLC (US) | 2017-01-18 | — | — | EP | disclosed |
| WO-2015138276-A2 | RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC (US) | 2015-09-17 | — | — | WO | disclosed |