Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 19/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998824 | 0.81 | KDM1A (0.59) | KDM1A | |
| SCHEMBL17063357 | 0.80 | HTR2A (0.47) | KDM1A | |
| Hydrochloric Acid SCHEMBL7951984 | 0.80 | KDM1A (0.58) | KDM1A | |
| SCHEMBL3135567 | 0.79 | NPY5R (0.47) | KDM1A | |
| SCHEMBL4824315 | 0.78 | KDM1A (0.54) | KDM1A | |
| Hydrochloric Acid SCHEMBL17063302 | 0.78 | HTR2A (0.46) | KDM1A | |
| SCHEMBL4777232 | 0.77 | HTR6 (0.52) | — | |
| SCHEMBL17458540 | 0.76 | POLB (0.45) | — | |
| SCHEMBL17063332 | 0.75 | KDM4E (0.44) | — | |
| SCHEMBL22439463 | 0.74 | CNR2 (0.52) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116504-A2 | RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | Innov17 LLC (US) | 2017-01-18 | — | — | EP | disclosed |
| WO-2015138276-A2 | RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC (US) | 2015-09-17 | — | — | WO | disclosed |