Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282789 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL10991202 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL30944287 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL219725 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL16437413 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9AMAPTALDH1A1TP53 | |
| SCHEMBL18038426 | 0.79 | CYP3A4 (0.50) | SMN1; SMN2RAB9AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL25424554 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL30720790 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL219616 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL18791398 | 0.78 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9AMAPTCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124205-A1 | MODULATORS OF BETA CATENIN AND USES THEREOF | DEWPOINT THERAPEUTICS INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-10005774-B2 | Syk inhibitors | GILEAD SCIENCES, INC. (US) | 2018-06-26 | — | — | US | disclosed |
| US-20160368918-A1 | SYK INHIBITORS | Kronos Bio, Inc. | 2016-12-22 | — | — | US | disclosed |
| US-9376441-B2 | Substituted pyrrolidines as SYK inhibitors | GILEAD SCIENCES, INC. (US) | 2016-06-28 | — | — | US | disclosed |
| US-9181234-B2 | Antibacterial compounds | BIOTA EUROPE LTD. (GB) | 2015-11-10 | — | — | US | disclosed |
| US-20150038488-A1 | SYK INHIBITORS | Kronos Bio, Inc. | 2015-02-05 | — | — | US | disclosed |
| EP-2034997-B1 | ANTIBACTERIAL COMPOSITIONS | BIOTA EUROPE LTD (GB) | 2012-10-17 | — | — | EP | disclosed |
| US-20120088750-A1 | ANTIBACTERIAL COMPOUNDS | BIOTA EUROPE LTD. (GB) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088750-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, NISCH, LSS | SMN1; SMN2 4065/4885RAB9A 915/4885MAPT 3134/4885 |
| US-20260124205-A1 | MODULATORS OF BETA CATENIN AND USES THEREOF | CTNNB1, CTNNA1, CTNND1 | SMN1; SMN2 2898/4885RAB9A 2550/4885MAPT 4207/4885 |
| US-20150038488-A1 | SYK INHIBITORS | SYK, BTK, LYN | SMN1; SMN2 3200/4885RAB9A 3263/4885MAPT 4092/4885 |
| US-20160368918-A1 | SYK INHIBITORS | SYK, BTK, LYN | SMN1; SMN2 3271/4885RAB9A 3273/4885MAPT 4131/4885 |
| US-10005774-B2 | Syk inhibitors | SYK, BTK, LYN | SMN1; SMN2 3271/4885RAB9A 3273/4885MAPT 4131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.