Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30720790 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2AXLGFERALDH1A1TP53 | |
| SCHEMBL25423809 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2AXLGFERALDH1A1TP53 | |
| SCHEMBL1748005 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2AXLGFERALDH1A1TP53 | |
| SCHEMBL30389176 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2AXLGFERALDH1A1TP53 | |
| SCHEMBL1282789 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2AXLGFERALDH1A1TP53 | |
| SCHEMBL219725 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2AXLGFERALDH1A1TP53 | |
| SCHEMBL1707911 | 0.78 | SMN1; SMN2 (0.68) | SMN1; SMN2AXLGFERALDH1A1TP53 | |
| SCHEMBL219616 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2AXLGFERALDH1A1TP53 | |
| SCHEMBL27264665 | 0.77 | SCN4A (0.49) | SMN1; SMN2AXLGFERALDH1A1TP53 | |
| SCHEMBL18038426 | 0.75 | CYP3A4 (0.50) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026479-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2023118267-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | GALECTO BIOTECH AB (DK) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023118267-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | GALECTO BIOTECH AB (DK) | 2023-06-29 | — | — | WO | disclosed |