Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707798 | 0.85 | — | — | |
| SCHEMBL1707831 | 0.84 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10010199 | 0.81 | FFAR1 (0.41) | — | |
| SCHEMBL1707914 | 0.80 | MAPT (0.33) | NPC1RAB9ASMN1; SMN2GAAHSD17B10 | |
| SCHEMBL1708212 | 0.80 | — | — | |
| SCHEMBL1707934 | 0.80 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2GAAHSD17B10 | |
| SCHEMBL1708580 | 0.78 | — | — | |
| SCHEMBL1708285 | 0.78 | LMNA (0.31) | SMN1; SMN2 | |
| SCHEMBL1708230 | 0.77 | — | — | |
| SCHEMBL1707936 | 0.76 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |