Syringic Acid

Syringic Acid

SCHEMBL17079864

COc1cc(C(=O)O)cc(OC)c1O.COc1cc(C(=O)O)ccc1O.COc1cc(C=O)cc(OC)c1O.COc1cc(C=O)ccc1O.O=C(O)c1ccc(O)cc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.59
ALDH1A1 P00352 2/20 0.59
TRIM24 O15164 1/20 0.59
HPGD P15428 1/20 0.59
ALDH5A1 P51649 1/20 0.59
ABAT P80404 1/20 0.59
TRIM33 Q9UPN9 1/20 0.59
HTT P42858 1/20 0.59
CXCL12 P48061 1/20 0.56
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA3 P07451 2/20 0.52
PKM P14618 2/20 0.52
CA4 P22748 2/20 0.52
CA6 P23280 2/20 0.52
CA5A P35218 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vanillic Acid SCHEMBL6304148 0.89 TDP1 (0.76) TDP1ALDH1A1TRIM24HPGDALDH5A1
Vanillic Acid SCHEMBL31482267 0.89 TDP1 (0.76) TDP1ALDH1A1TRIM24HPGDALDH5A1
Vanillic Acid SCHEMBL21243287 0.85 TDP1 (0.69) TDP1ALDH1A1TRIM24HPGDALDH5A1
Vanillic Acid SCHEMBL15111200 0.84 TDP1 (0.68) TDP1ALDH1A1TRIM24HPGDALDH5A1
Gallic Acid SCHEMBL28376611 0.83 ALDH1A1 (0.71) TDP1ALDH1A1TRIM24HPGDALDH5A1
Vanillic Acid SCHEMBL6561163 0.83 HTT (0.86) TDP1HTTCXCL12CA12CA1
Syringaldehyde SCHEMBL7897948 0.83 ALDH1A1 (0.86) TDP1ALDH1A1TRIM24HPGDALDH5A1
Methyl Vanillate SCHEMBL1491815 0.83 ALDH1A1 (0.66) TDP1ALDH1A1TRIM24HPGDALDH5A1
Syringic Acid SCHEMBL8147496 0.81 ALDH1A1 (0.56) TDP1ALDH1A1TRIM24HPGDALDH5A1
Vanillin SCHEMBL8378629 0.80 ALDH1A1 (0.86) TDP1ALDH1A1TRIM24HPGDALDH5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015138563-A1 SELECTIVE C-O BOND CLEAVAGE OF OXIDIZED LIGNIN AND LIGNIN-TYPE MATERIALS INTO SIMPLE AROMATIC COMPOUNDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-09-17 WO disclosed