Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | BMI1 | P35226 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708082 | 0.93 | FFAR1 (0.36) | FFAR1MAPTPPARDTP53 | |
| SCHEMBL1707877 | 0.93 | FFAR1 (0.42) | FFAR1PPARD | |
| SCHEMBL1708121 | 0.91 | FFAR1 (0.35) | FFAR1MAPTPPARDBMI1TP53 | |
| SCHEMBL1707998 | 0.91 | FFAR1 (0.37) | FFAR1MAPTPPARD | |
| SCHEMBL1708157 | 0.91 | FFAR1 (0.38) | FFAR1MAPTPPARDTP53L3MBTL1 | |
| SCHEMBL1708300 | 0.91 | FFAR1 (0.38) | FFAR1MAPTPPARDL3MBTL1 | |
| SCHEMBL10291340 | 0.89 | MAPT (0.34) | MAPTBMI1TP53 | |
| SCHEMBL1708439 | 0.87 | FFAR1 (0.40) | FFAR1MAPTPPARD | |
| SCHEMBL1708153 | 0.87 | SMN1; SMN2 (0.40) | FFAR1MAPTPPARDTP53 | |
| SCHEMBL10291339 | 0.87 | BMI1 (0.34) | FFAR1MAPTBMI1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |