Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10009045 | 0.93 | FFAR1 (0.42) | FFAR1PPARDPPARG | |
| SCHEMBL1708247 | 0.93 | FFAR1 (0.42) | FFAR1PPARDPPARG | |
| SCHEMBL1708262 | 0.91 | FFAR1 (0.35) | FFAR1PPARDPPARGMAPTALDH1A1 | |
| SCHEMBL1708028 | 0.91 | FFAR1 (0.37) | FFAR1PPARDMAPT | |
| SCHEMBL1708157 | 0.91 | FFAR1 (0.38) | FFAR1PPARDMAPTALDH1A1 | |
| SCHEMBL10291804 | 0.89 | MAPT (0.33) | FFAR1MAPTALDH1A1PKMIDH1 | |
| SCHEMBL1708439 | 0.87 | FFAR1 (0.40) | FFAR1PPARDMAPTALDH1A1 | |
| SCHEMBL10291806 | 0.87 | MAPT (0.34) | MAPTALDH1A1PKMIDH1 | |
| SCHEMBL1708250 | 0.86 | ALDH1A1 (0.34) | FFAR1MAPTALDH1A1PKMIDH1 | |
| SCHEMBL1708135 | 0.86 | FFAR1 (0.39) | FFAR1PPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |