Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 15/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707935 | 1.00 | LMNA (0.35) | LMNAFFAR1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL1708117 | 1.00 | LMNA (0.35) | LMNAFFAR1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL1708024 | 0.93 | LMNA (0.34) | LMNAFFAR1SMN1; SMN2TSHR | |
| SCHEMBL1707975 | 0.93 | LMNA (0.34) | LMNAFFAR1SMN1; SMN2TSHR | |
| SCHEMBL1708282 | 0.93 | FFAR1 (0.34) | LMNAFFAR1SMN1; SMN2PPARD | |
| SCHEMBL1708279 | 0.93 | FFAR1 (0.34) | LMNAFFAR1PPARD | |
| SCHEMBL1707945 | 0.93 | FFAR1 (0.34) | LMNAFFAR1PPARD | |
| SCHEMBL1708344 | 0.93 | FFAR1 (0.34) | LMNAFFAR1PPARD | |
| SCHEMBL10010835 | 0.92 | FFAR1 (0.36) | FFAR1PPARD | |
| SCHEMBL10009726 | 0.92 | FFAR1 (0.36) | FFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |