Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.39 |
| ▸ | TACR1 | P25103 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096200 | 1.00 | SLC6A9 (0.47) | SLC6A9KCNH2TACR1MEN1KMT2A | |
| SCHEMBL1095224 | 1.00 | SLC6A9 (0.47) | SLC6A9KCNH2TACR1MEN1KMT2A | |
| SCHEMBL17081973 | 1.00 | SLC6A9 (0.47) | SLC6A9KCNH2TACR1MEN1KMT2A | |
| SCHEMBL1096250 | 1.00 | SLC6A9 (0.47) | SLC6A9KCNH2TACR1MEN1KMT2A | |
| SCHEMBL1096198 | 1.00 | SLC6A9 (0.47) | SLC6A9KCNH2TACR1MEN1KMT2A | |
| SCHEMBL1096253 | 1.00 | SLC6A9 (0.47) | SLC6A9KCNH2TACR1MEN1KMT2A | |
| SCHEMBL1094750 | 0.87 | SLC6A9 (0.47) | SLC6A9 | |
| SCHEMBL1095057 | 0.84 | SLC6A9 (0.50) | SLC6A9 | |
| SCHEMBL1096171 | 0.77 | SLC6A9 (0.52) | SLC6A9 | |
| SCHEMBL1095577 | 0.77 | SLC6A9 (0.52) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585456-B1 | AMIDO-TROPANE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2015-09-16 | — | — | EP | disclosed |