Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 12/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570194 | 1.00 | HSD11B1 (0.42) | HSD11B1NOTUMPTPN11HTR1ADRD2 | |
| SCHEMBL549455 | 1.00 | HSD11B1 (0.42) | HSD11B1NOTUMPTPN11HTR1ADRD2 | |
| SCHEMBL550649 | 1.00 | HSD11B1 (0.42) | HSD11B1NOTUMPTPN11HTR1ADRD2 | |
| SCHEMBL2699453 | 1.00 | HSD11B1 (0.42) | HSD11B1NOTUMPTPN11HTR1ADRD2 | |
| SCHEMBL2698077 | 1.00 | HSD11B1 (0.42) | HSD11B1NOTUMPTPN11HTR1ADRD2 | |
| SCHEMBL551282 | 1.00 | HSD11B1 (0.42) | HSD11B1NOTUMPTPN11HTR1ADRD2 | |
| SCHEMBL550698 | 1.00 | HSD11B1 (0.42) | HSD11B1NOTUMPTPN11HTR1ADRD2 | |
| SCHEMBL550442 | 0.92 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1A | |
| SCHEMBL550441 | 0.92 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1A | |
| SCHEMBL549967 | 0.92 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812005-B1 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2015-09-16 | — | — | EP | disclosed |