Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 13/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | LCAT | P04180 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL550836 | 0.92 | LCAT (0.43) | HSD11B1HRH3EPHX2LCATTRPV1 | |
| SCHEMBL550164 | 0.92 | LCAT (0.43) | HSD11B1HRH3EPHX2LCATTRPV1 | |
| SCHEMBL550163 | 0.92 | LCAT (0.43) | HSD11B1HRH3EPHX2LCATTRPV1 | |
| SCHEMBL550071 | 0.92 | LCAT (0.43) | HSD11B1HRH3EPHX2LCATTRPV1 | |
| SCHEMBL2700133 | 0.92 | LCAT (0.43) | HSD11B1HRH3EPHX2LCATTRPV1 | |
| SCHEMBL550221 | 0.92 | LCAT (0.43) | HSD11B1HRH3EPHX2LCATTRPV1 | |
| SCHEMBL550072 | 0.92 | LCAT (0.43) | HSD11B1HRH3EPHX2LCATTRPV1 | |
| SCHEMBL2701622 | 0.92 | LCAT (0.43) | HSD11B1HRH3EPHX2LCATTRPV1 | |
| SCHEMBL2700135 | 0.92 | LCAT (0.43) | HSD11B1HRH3EPHX2LCATTRPV1 | |
| SCHEMBL549583 | 0.91 | EPHX2 (0.41) | HSD11B1HRH3EPHX2LCATTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812005-B1 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2015-09-16 | — | — | EP | disclosed |