Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | DCK | P27707 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26847502 | 0.86 | CYP11B1 (0.39) | CYP11B1CYP11B2PIK3CGPIM1DCK | |
| SCHEMBL18569269 | 0.83 | CYP11B1 (0.38) | CYP11B1CYP11B2PIK3CGPIM1DCK | |
| SCHEMBL17082451 | 0.83 | CYP11B1 (0.38) | CYP11B1CYP11B2PIK3CGPIM1DCK | |
| SCHEMBL17589770 | 0.83 | CYP11B1 (0.38) | CYP11B1CYP11B2PIK3CGPIM1DCK | |
| SCHEMBL17641052 | 0.80 | PIM1 (0.38) | CYP11B1CYP11B2PIK3CGPIM1DCK | |
| SCHEMBL290713 | 0.79 | APP (0.38) | CYP11B1CYP11B2PIK3CGPIM1DYRK1A | |
| SCHEMBL18569311 | 0.79 | APP (0.35) | CYP11B1CYP11B2PIK3CGPIM1DYRK1A | |
| Hydrochloric Acid SCHEMBL17629274 | 0.78 | APP (0.37) | CYP11B1CYP11B2PIK3CGPIM1DYRK1A | |
| SCHEMBL17488376 | 0.77 | PIM1 (0.40) | CYP11B1CYP11B2PIK3CGPIM1DYRK1A | |
| SCHEMBL12040234 | 0.75 | CYP3A4 (0.53) | CYP19A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614825-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-2604268-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |