Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10066410 | 0.81 | CYP11B1 (0.45) | CYP11B2CYP11B1NOS1PIK3CGP2RX3 | |
| SCHEMBL290909 | 0.78 | PIK3CG (0.35) | PIM1CYP11B2CYP11B1PIK3CGPOLQ | |
| SCHEMBL18569045 | 0.78 | PIM1 (0.35) | PIM1CYP11B2CYP11B1PIK3CGPOLQ | |
| SCHEMBL2098130 | 0.77 | MET (0.52) | PIM1METCTSA | |
| SCHEMBL17082452 | 0.77 | CYP11B1 (0.39) | PIM1CYP11B2CYP11B1PIK3CGPARP10 | |
| SCHEMBL2090445 | 0.76 | APP (0.44) | METNOS1CTSA | |
| SCHEMBL290908 | 0.75 | CYP11B2 (0.38) | PIM1CYP11B2CYP11B1 | |
| SCHEMBL26847502 | 0.74 | CYP11B1 (0.39) | PIM1CYP11B2CYP11B1PIK3CGDYRK1A | |
| SCHEMBL14817176 | 0.73 | HSD17B1 (0.47) | PIM1CYP11B2CYP11B1PIK3CGPARP10 | |
| SCHEMBL17823650 | 0.72 | GRM5 (0.41) | METPOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604267-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2016-02-03 | — | — | EP | disclosed |