Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706962 | 0.84 | LTA4H (0.69) | POLBTRPV1LTA4HTP53MAPT | |
| SCHEMBL8157378 | 0.83 | MAPT (0.60) | POLBMAPTKMT2AHDAC4HDAC1 | |
| SCHEMBL31203466 | 0.81 | HDAC4 (0.69) | LTA4HHDAC4HDAC1HDAC7HDAC11 | |
| SCHEMBL16398136 | 0.81 | MAPT (0.67) | POLBTRPV1LTA4HMAPTKMT2A | |
| SCHEMBL8178246 | 0.80 | HDAC4 (0.72) | LTA4HHDAC4HDAC1HDAC7HDAC11 | |
| SCHEMBL4837637 | 0.80 | HDAC4 (0.72) | LTA4HHDAC4HDAC1HDAC7HDAC11 | |
| SCHEMBL14934835 | 0.80 | HDAC4 (0.72) | LTA4HHDAC4HDAC1HDAC7HDAC11 | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.80 | POLB (0.78) | POLBTP53MAPTRAB9AKDM1A | |
| SCHEMBL1160190 | 0.80 | POLB (0.61) | POLBTP53MAPTRAB9AGAA | |
| SCHEMBL9164909 | 0.80 | MEN1 (0.54) | POLBRAB9AKMT2AHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365508-B2 | Aroyl thiourea derivatives | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2016-06-14 | — | — | US | disclosed |
| EP-2440522-B1 | AROYLTHIOUREA AND ARYLTHIOCARBONYLUREA DERIVATIVES | UNIV DUNDEE (GB) | 2014-11-12 | — | — | EP | disclosed |
| US-20120149778-A1 | COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE | 2012-06-14 | — | — | US | disclosed |
| EP-2440522-A2 | AROYLTHIOUREA AND ARYLTHIOCARBONYLUREA DERIVATIVES | University Court of The University of Dundee (GB) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010142956-A2 | COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149778-A1 | COMPOUNDS | AR, NR5A1, NAT1 | POLB 2188/4885TRPV1 1425/4885LTA4H 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.