Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.84 |
| ▸ | MAPT | P10636 | 5/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18406168 | 0.91 | KDM4E (0.98) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL17079910 | 0.84 | FGFR1 (0.72) | KDM4EMAPTSMN1; SMN2ALDH1A1RXFP1 | |
| SCHEMBL17079912 | 0.76 | SHMT2 (0.54) | KDM4EMAPTSMN1; SMN2ALDH1A1SHMT2 | |
| SCHEMBL17084507 | 0.75 | FGFR1 (0.60) | KDM4EMAPTSMN1; SMN2ALDH1A1RXFP1 | |
| SCHEMBL17079920 | 0.75 | CSNK2A2 (0.79) | KDM4EMAPTSMN1; SMN2ALDH1A1RXFP1 | |
| SCHEMBL4519850 | 0.70 | KMT2A (0.66) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL15426162 | 0.70 | FGFR1 (0.67) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4517192 | 0.70 | KDM4E (0.64) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL18540842 | 0.69 | MAPT (0.66) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL13164992 | 0.68 | KDM4E (0.59) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170022215-A1 | Compounds for Eradicating or Inhibiting Proliferation of Cancer Stem Cells | GODAVARI BIOREFINERIES LIMITED (IN) | 2017-01-26 | — | — | US | disclosed |
| US-20170022215-A1 | Compounds for Eradicating or Inhibiting Proliferation of Cancer Stem Cells | GODAVARI BIOREFINERIES LIMITED (IN) | 2017-01-26 | — | — | US | disclosed |
| WO-2015136556-A2 | COMPOUNDS FOR ERADICATING OR INHIBITING PROLIFERATION OF CANCER STEM CELLS | GODAVARI BIOREFINERIES LIMITED (IN) | 2015-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022215-A1 | Compounds for Eradicating or Inhibiting Proliferation of Cancer Stem Cells | MCL1, MKI67, BCL2 | KDM4E 1681/4885MAPT 4753/4885SMN1; SMN2 4090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.