Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708003 | 0.90 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ABL1KMT2A | |
| SCHEMBL1283007 | 0.87 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA | |
| SCHEMBL18365218 | 0.85 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2ABL1KMT2A | |
| SCHEMBL1282966 | 0.84 | ABL1 (0.56) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA | |
| SCHEMBL1708588 | 0.83 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ABL1KMT2A | |
| SCHEMBL1708006 | 0.80 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ABL1KMT2A | |
| SCHEMBL12469564 | 0.80 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA | |
| SCHEMBL1282245 | 0.79 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA | |
| SCHEMBL220748 | 0.78 | ABL1 (0.52) | ABL1 | |
| SCHEMBL1282103 | 0.78 | ABL1 (0.43) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181234-B2 | Antibacterial compounds | BIOTA EUROPE LTD. (GB) | 2015-11-10 | — | — | US | disclosed |
| US-20120088750-A1 | ANTIBACTERIAL COMPOUNDS | BIOTA EUROPE LTD. (GB) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088750-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, NISCH, LSS | NPC1 1032/4885RAB9A 915/4885SMN1; SMN2 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.