SCHEMBL1708679

SCHEMBL1708679

NC(=O)COc1ccccc1C1=Nc2ccccc2NC(=O)C1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
TP53 P04637 1/20 0.46
MAPT P10636 4/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HTT P42858 2/20 0.40
LMNA P02545 1/20 0.40
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
ADORA1 P30542 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30702314 1.00 ALDH1A1 (0.51) ALDH1A1TP53MAPTMEN1KMT2A
SCHEMBL1754965 0.90 ALDH1A1 (0.55) ALDH1A1TP53MAPTMEN1KMT2A
SCHEMBL13056588 0.85 ALDH1A1 (0.46) ALDH1A1TP53MAPTMEN1KMT2A
SCHEMBL1754963 0.85 PTPN1 (0.47) ALDH1A1TP53MAPTMEN1KMT2A
SCHEMBL13056589 0.82 ALDH1A1 (0.45) ALDH1A1TP53MAPTMEN1KMT2A
SCHEMBL14030155 0.82 ALDH1A1 (0.45) ALDH1A1TP53MAPTMEN1KMT2A
SCHEMBL16202235 0.79 ALDH1A1 (0.59) ALDH1A1TP53MAPTMEN1KMT2A
SCHEMBL13056593 0.79 ALDH1A1 (0.41) ALDH1A1TP53MAPTSMN1; SMN2
SCHEMBL13056590 0.79 ALDH1A1 (0.43) ALDH1A1TP53MAPTMEN1KMT2A
SCHEMBL20118123 0.78 ALDH1A1 (0.40) ALDH1A1TP53MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240123045-A1 NONAUTOLOGOUS MULTI-STRESSED CANCER CELLS AND USES THEREOF FOR VACCINATING AND TREATING CANCERS BRENUS PHARMA (FR) 2024-04-18 US claimed
EP-2686438-B1 A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFOR VENTANA MED SYST INC (US) 2018-04-18 EP claimed
US-9562259-B2 Method of analyzing chromosomal inversions VENTANA MEDICAL SYSTEMS, INC. (US) 2017-02-07 US claimed
EP-2686438-A1 A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFORE Ventana Medical Systems, Inc. (US) 2014-01-22 EP claimed
EP-2539466-A1 CYTOGENIC ANALYSIS OF METAPHASE CHROMOSOMES Ventana Medical Systems, Inc. (US) 2013-01-02 EP claimed
EP-2539355-A1 POLYTAG PROBES Ventana Medical Systems, Inc. (US) 2013-01-02 EP claimed
US-20120301885-A1 CYTOGENIC ANALYSIS OF METAPHASE CHROMOSOMES TANG LEI (US) 2012-11-29 US claimed
US-20120301886-A1 POLYTAG PROBES VENTANA MEDICAL SYSTEMS, INC. 2012-11-29 US claimed
US-20120237930-A1 METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFORE VENTANA MEDICAL SYSTEMS, INC. 2012-09-20 US claimed
WO-2012123387-A1 A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFORE F. HOFFMANN-LA ROCHE AG (CH) 2012-09-20 WO claimed
US-20250223640-A1 METHODS AND KITS FOR DETECTION OF METHYLATION STATUS OSLO UNIVERSITETSSYKEHUS HF (NO) 2025-07-10 US disclosed
EP-4574995-A2 METHODS AND KITS FOR DETECTION OF METHYLATION STATUS Oslo Universitetssykehus HF (NO) 2025-06-25 EP disclosed
EP-3904533-B1 METHOD FOR DETECTION OF HYDROXYMETHYLATION STATUS UNIV OSLO HF (NO) 2025-02-26 EP disclosed
US-12126880-B2 Digitally enhanced microscopy for multiplexed histology VENTANA MEDICAL SYSTEMS, INC. (US) 2024-10-22 US disclosed
US-20240123045-A1 NONAUTOLOGOUS MULTI-STRESSED CANCER CELLS AND USES THEREOF FOR VACCINATING AND TREATING CANCERS BRENUS PHARMA (FR) 2024-04-18 US disclosed
US-7695929-B2 Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits VENTANA MEDICAL SYSTEMS, INC. (US) 2010-04-13 US disclosed
EP-2078197-A2 HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE Ventana Medical Systems, Inc. (US) 2009-07-15 EP disclosed
US-20080268462-A1 Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits VENTANA MEDICAL SYSTEMS, INC. 2008-10-30 US disclosed
WO-2008063378-A9 HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE VENTANA MED SYST INC (US) 2008-07-31 WO disclosed
WO-2008063378-A2 HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE VENTANA MEDICAL SYSTEMS, INC. (US) 2008-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080268462-A1 Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits HRH4, CRBN, NCDN ALDH1A1 2096/4885TP53 3304/4885MAPT 3454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.