Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17078623 | 0.86 | HDAC1 (0.58) | KMT2AMEN1TP53ALDH1A1GAA | |
| SCHEMBL17086794 | 0.85 | HDAC1 (0.53) | HDAC1HDAC4KCNH2HDAC6 | |
| SCHEMBL20432705 | 0.80 | HDAC1 (0.57) | KMT2AMEN1ALDH1A1HDAC1HTT | |
| SCHEMBL20432707 | 0.80 | HDAC1 (0.57) | KMT2AMEN1ALDH1A1HDAC1HTT | |
| SCHEMBL17078892 | 0.80 | HDAC1 (0.58) | KMT2AMEN1TP53ALDH1A1HDAC1 | |
| SCHEMBL20433056 | 0.80 | HDAC1 (0.58) | KMT2AMEN1TP53ALDH1A1HDAC1 | |
| SCHEMBL17078526 | 0.80 | HDAC1 (0.58) | KMT2AMEN1TP53ALDH1A1HDAC1 | |
| SCHEMBL20432768 | 0.78 | HDAC1 (0.70) | HDAC1HDAC4KCNH2HDAC6 | |
| SCHEMBL17086723 | 0.77 | HDAC1 (0.53) | KMT2AALDH1A1HDAC1HDAC4KCNH2 | |
| SCHEMBL17086801 | 0.75 | HDAC1 (0.47) | HDAC1HDAC4KCNH2HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015137750-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-09-17 | — | — | WO | disclosed |