Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17086800 | 0.93 | HIF1A (0.44) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL17078835 | 0.87 | HDAC1 (0.58) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL17086795 | 0.84 | HDAC1 (0.40) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL20421030 | 0.82 | HDAC1 (0.58) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL17078680 | 0.82 | HDAC1 (0.58) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL20432854 | 0.82 | HDAC1 (0.58) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL17086794 | 0.81 | HDAC1 (0.53) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL17078539 | 0.80 | HDAC6 (0.55) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL20432768 | 0.78 | HDAC1 (0.70) | HDAC1HDAC4KCNH2HDAC6HDAC8 | |
| SCHEMBL17078717 | 0.78 | TSHR (0.47) | HDAC1HDAC6TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015137750-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-09-17 | — | — | WO | disclosed |