Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17087031 | 0.93 | GLS (0.68) | GLS | |
| SCHEMBL18137306 | 0.93 | GLS (0.69) | GLS | |
| SCHEMBL16384713 | 0.92 | GLS (0.78) | GLS | |
| SCHEMBL16379545 | 0.92 | GLS (0.73) | GLS | |
| SCHEMBL17087061 | 0.91 | GLS (0.70) | GLS | |
| SCHEMBL18122527 | 0.90 | GLS (0.77) | GLS | |
| SCHEMBL16379547 | 0.90 | GLS (0.68) | GLS | |
| SCHEMBL15782980 | 0.90 | GLS (0.69) | GLS | |
| SCHEMBL17087030 | 0.89 | GLS (0.66) | GLS | |
| SCHEMBL18137193 | 0.89 | GLS (0.69) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015138902-A1 | COMBINATION THERAPY WITH GLUTAMINASE INHIBITORS | CALITHERA BIOSCIENCES, INC. (US) | 2015-09-17 | — | — | WO | disclosed |