Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10010075 | 0.85 | PPARG (0.41) | FFAR1 | |
| SCHEMBL3718334 | 0.80 | PPARG (0.33) | FFAR1 | |
| SCHEMBL1708709 | 0.79 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL1707962 | 0.79 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL10011908 | 0.77 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL10009300 | 0.75 | PPARD (0.39) | FFAR1 | |
| SCHEMBL10010709 | 0.72 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL1708705 | 0.72 | FFAR1 (0.34) | FFAR1 | |
| SCHEMBL10009432 | 0.71 | PPARG (0.36) | FFAR1 | |
| SCHEMBL1708717 | 0.71 | TSHR (0.34) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |