Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17322726 | 0.97 | ADRB2 (0.51) | ADRB2HTR1APTPN1PARP1BRD4 | |
| SCHEMBL15298605 | 0.97 | ADRB2 (0.51) | ADRB2HTR1APTPN1PARP1BRD4 | |
| SCHEMBL16671983 | 0.94 | ADRB2 (0.53) | ADRB2HTR1APTPN1PARP1BRD4 | |
| SCHEMBL11302387 | 0.91 | ADRB2 (0.46) | ADRB2HTR1APTPN1PARP1BRD4 | |
| SCHEMBL13991453 | 0.89 | ADRB2 (0.52) | ADRB2HTR1APTPN1PARP1BRD4 | |
| SCHEMBL15271642 | 0.88 | ADRB2 (0.55) | ADRB2HTR1APTPN1PARP1BRD4 | |
| SCHEMBL15271648 | 0.88 | ADRB2 (0.55) | ADRB2HTR1APTPN1PARP1BRD4 | |
| SCHEMBL15271632 | 0.88 | ADRB2 (0.55) | ADRB2HTR1APTPN1PARP1BRD4 | |
| SCHEMBL18020661 | 0.88 | ADRB2 (0.45) | ADRB2HTR1APTPN1PARP1BRD4 | |
| SCHEMBL31551164 | 0.88 | ADRB2 (0.58) | ADRB2HTR1APTPN1PARP1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9140706-B2 | Labeling reagents and methods of their use | Life Technologies Corporation (US) | 2015-09-22 | — | — | US | disclosed |