Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 2/20 | 0.42 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20089218 | 0.84 | NR1D1 (0.51) | NR1D1SLC10A6MEN1KMT2APTPN1 | |
| SCHEMBL17089905 | 0.82 | CA1 (0.45) | SLC10A6MEN1KMT2APTPN1TDP1 | |
| SCHEMBL17089904 | 0.82 | KMT2A (0.46) | SLC10A6MEN1KMT2APTPN1TDP1 | |
| SCHEMBL17089909 | 0.82 | KMT2A (0.46) | SLC10A6MEN1KMT2APTPN1TDP1 | |
| SCHEMBL530068 | 0.82 | NR1D1 (0.43) | NR1D1MEN1KMT2APTPN1TDP1 | |
| SCHEMBL530360 | 0.81 | NR1D1 (0.46) | NR1D1MEN1KMT2APTPN1TDP1 | |
| SCHEMBL10076735 | 0.81 | NR1D1 (0.42) | NR1D1MEN1KMT2APTPN1TDP1 | |
| SCHEMBL31618146 | 0.79 | KMT2A (0.46) | MEN1KMT2APTPN1F2PRSS1 | |
| SCHEMBL16558058 | 0.76 | NR1D1 (0.53) | NR1D1MEN1KMT2APTPN1CA1 | |
| SCHEMBL29238398 | 0.76 | MEN1 (0.51) | SLC10A6MEN1KMT2APTPN1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139615-B2 | High-affinity, dimeric inhibitors of PSD-95 as efficient neuroprotectants against ischemic brain damage and for treatment of pain | UNIVERSITY OF COPENHAGEN (DK) | 2015-09-22 | — | — | US | disclosed |