Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17089969 | 0.88 | PTPRB (0.42) | PKMHSD17B10ALDH1A1 | |
| SCHEMBL10113481 | 0.86 | NR1H4 (0.51) | NR1H4PKMALDH1A1HDAC3MAPK1 | |
| SCHEMBL13438596 | 0.85 | HPGD (0.46) | FFAR1MAPK1SMN1; SMN2FFAR4 | |
| SCHEMBL11934794 | 0.85 | HPGD (0.46) | FFAR1MAPK1SMN1; SMN2FFAR4 | |
| SCHEMBL13565863 | 0.83 | EPHX1 (0.43) | FFAR1ALDH1A1FFAR4 | |
| SCHEMBL13564843 | 0.83 | HPGD (0.47) | FFAR1MAPK1SMN1; SMN2FFAR4 | |
| SCHEMBL11935070 | 0.83 | FFAR1 (0.47) | NR1H4FFAR1PKMHSD17B10ALDH1A1 | |
| SCHEMBL13565491 | 0.81 | MEN1 (0.36) | FFAR1ALDH1A1MAPK1FFAR4 | |
| SCHEMBL11239458 | 0.80 | S1PR1 (0.62) | NR1H4FFAR1HSD17B10ALDH1A1S1PR1 | |
| SCHEMBL11229424 | 0.80 | S1PR1 (0.62) | NR1H4FFAR1HSD17B10ALDH1A1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |