Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565760 | 1.00 | USP30 (0.33) | USP30KDM4EHTTLMNANPY5R | |
| SCHEMBL17090175 | 0.87 | CNR1 (0.36) | NPY5RDRD2HTR2ADRD3CNR2 | |
| SCHEMBL13565620 | 0.87 | CNR1 (0.36) | NPY5RDRD2HTR2ADRD3CNR2 | |
| SCHEMBL13565905 | 0.87 | NPY5R (0.37) | NPY5R | |
| SCHEMBL17090240 | 0.87 | NPY5R (0.37) | NPY5R | |
| SCHEMBL13565047 | 0.85 | LRRK2 (0.35) | TRPV1SCN5AHTR2ADRD3CNR2 | |
| SCHEMBL17090183 | 0.85 | LRRK2 (0.35) | TRPV1SCN5AHTR2ADRD3CNR2 | |
| SCHEMBL13565030 | 0.83 | USP30 (0.39) | USP30KDM4EHTTLMNACNR2 | |
| SCHEMBL10114332 | 0.82 | NPY5R (0.47) | USP30KDM4ELMNANPY5R | |
| SCHEMBL10133409 | 0.82 | NPY5R (0.47) | USP30KDM4ELMNANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |