Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 11/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564942 | 1.00 | TOP1 (0.39) | TOP1GRIA2CYP2C19CYP1A2KMT2A | |
| SCHEMBL13565095 | 0.85 | TOP1 (0.39) | TOP1 | |
| SCHEMBL17090358 | 0.85 | TOP1 (0.39) | TOP1 | |
| SCHEMBL13565171 | 0.82 | AAK1 (0.41) | GRIA2CYP1A2KMT2AMEN1 | |
| SCHEMBL13565968 | 0.82 | TAAR1 (0.40) | GRIA2CYP1A2 | |
| SCHEMBL17090371 | 0.82 | TAAR1 (0.40) | GRIA2CYP1A2 | |
| SCHEMBL13439168 | 0.81 | GRIA2 (0.44) | GRIA2CYP1A2 | |
| SCHEMBL13565446 | 0.81 | GRIA2 (0.44) | GRIA2CYP1A2 | |
| SCHEMBL11941022 | 0.81 | GRIA2 (0.44) | GRIA2CYP1A2 | |
| SCHEMBL17090049 | 0.81 | GRIA2 (0.42) | GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |