Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565765 | 1.00 | F10 (0.36) | F10BRD4HSD17B10HTTMEN1 | |
| SCHEMBL13565132 | 0.88 | NR1H4 (0.40) | F10BRD4MEN1NPC1MAPT | |
| SCHEMBL13565482 | 0.88 | HDAC4 (0.41) | F10BRD4HSD17B10HTTMEN1 | |
| SCHEMBL17090309 | 0.88 | HDAC4 (0.41) | F10BRD4HSD17B10HTTMEN1 | |
| SCHEMBL17090000 | 0.88 | NR1H4 (0.40) | F10BRD4MEN1NPC1MAPT | |
| SCHEMBL13564825 | 0.86 | GRIA2 (0.38) | F10BRD4HSD17B10HTTMEN1 | |
| SCHEMBL13565615 | 0.86 | F10 (0.37) | F10BRD4MEN1NPC1MAPT | |
| SCHEMBL17090308 | 0.86 | F10 (0.37) | F10BRD4MEN1NPC1MAPT | |
| SCHEMBL11936203 | 0.85 | CNR2 (0.39) | F10HTTMEN1MAPTKMT2A | |
| SCHEMBL17090307 | 0.85 | THRB (0.42) | F10HTTMEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |