Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565039 | 0.89 | NPC1 (0.46) | CNR2CNR1DRD2HTR2ADRD3 | |
| SCHEMBL10114279 | 0.83 | SMN1; SMN2 (0.57) | HTTSMN1; SMN2TSHRKDM4ECYP3A4 | |
| SCHEMBL13565037 | 0.78 | MAPT (0.40) | CNR2HTTSMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL17090253 | 0.77 | NPC1 (0.38) | CNR2SMN1; SMN2KDM4ECYP3A4CYP2C19 | |
| SCHEMBL13565752 | 0.77 | NPC1 (0.38) | CNR2SMN1; SMN2KDM4ECYP3A4CYP2C19 | |
| SCHEMBL13439177 | 0.76 | CRHR1 (0.42) | CNR2 | |
| SCHEMBL11935441 | 0.76 | CRHR1 (0.42) | CNR2 | |
| SCHEMBL13564745 | 0.74 | KDM4E (0.51) | HTTSMN1; SMN2TSHRKDM4ECYP3A4 | |
| SCHEMBL17090323 | 0.74 | KDM4E (0.51) | HTTSMN1; SMN2TSHRKDM4ECYP3A4 | |
| SCHEMBL11935213 | 0.74 | MERTK (0.43) | CNR2CNR1HTTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |