Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565580 | 1.00 | GRIA2 (0.47) | GRIA2TP53MAPTCTSDBACE1 | |
| SCHEMBL17090199 | 0.88 | GRIA2 (0.43) | GRIA2TP53MAPT | |
| SCHEMBL13565582 | 0.88 | GRIA2 (0.43) | GRIA2TP53MAPT | |
| SCHEMBL13439061 | 0.87 | TP53 (0.41) | GRIA2TP53MAPTPOLBSMN1; SMN2 | |
| SCHEMBL11935338 | 0.87 | TP53 (0.41) | GRIA2TP53MAPTPOLBSMN1; SMN2 | |
| SCHEMBL11936249 | 0.86 | GRIA2 (0.40) | GRIA2TP53CTSDBACE1BACE2 | |
| SCHEMBL11936244 | 0.83 | GRIA2 (0.42) | GRIA2 | |
| SCHEMBL10114961 | 0.83 | TP53 (0.49) | GRIA2TP53MAPTPOLBSMN1; SMN2 | |
| SCHEMBL13204444 | 0.83 | TP53 (0.49) | GRIA2TP53MAPTPOLBSMN1; SMN2 | |
| SCHEMBL11936250 | 0.82 | GRIA2 (0.41) | GRIA2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |