Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565582 | 1.00 | GRIA2 (0.43) | GRIA2TP53AKR1C3LMNACA1 | |
| SCHEMBL13565580 | 0.88 | GRIA2 (0.47) | GRIA2TP53MAPT | |
| SCHEMBL17090202 | 0.88 | GRIA2 (0.47) | GRIA2TP53MAPT | |
| SCHEMBL11936215 | 0.88 | AKR1C3 (0.43) | TP53AKR1C3LMNACA1CA2 | |
| SCHEMBL13439060 | 0.86 | AKR1C3 (0.41) | TP53AKR1C3LMNACA1CA2 | |
| SCHEMBL11935342 | 0.86 | AKR1C3 (0.41) | TP53AKR1C3LMNACA1CA2 | |
| SCHEMBL11936249 | 0.85 | GRIA2 (0.40) | GRIA2TP53AKR1C3 | |
| SCHEMBL11936244 | 0.85 | GRIA2 (0.42) | GRIA2 | |
| SCHEMBL11936250 | 0.83 | GRIA2 (0.41) | GRIA2TP53 | |
| SCHEMBL13565425 | 0.83 | ALDH1A1 (0.41) | TP53LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |