Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 7/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935321 | 1.00 | CNR2 (0.51) | CNR2JAK2JAK1CNR1SLC22A12 | |
| SCHEMBL17090216 | 0.89 | KMT2A (0.44) | CNR2JAK2JAK1CNR1 | |
| SCHEMBL11935303 | 0.89 | KMT2A (0.44) | CNR2JAK2JAK1CNR1 | |
| SCHEMBL13564895 | 0.86 | CNR2 (0.47) | CNR2JAK2JAK1CNR1 | |
| SCHEMBL17090538 | 0.86 | CNR2 (0.47) | CNR2JAK2JAK1CNR1 | |
| SCHEMBL17090224 | 0.84 | CNR2 (0.40) | CNR2 | |
| SCHEMBL11935322 | 0.84 | CNR2 (0.40) | CNR2 | |
| SCHEMBL11936372 | 0.83 | CNR2 (0.46) | CNR2CNR1 | |
| SCHEMBL11936189 | 0.82 | NPY5R (0.49) | CNR2JAK2JAK1 | |
| SCHEMBL13105815 | 0.82 | CNR2 (0.43) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |