Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 8/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | GFER | P55789 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13462876 | 1.00 | GAA (0.41) | GAAL3MBTL1RAB9ANPC1MAPT | |
| SCHEMBL11942270 | 1.00 | GAA (0.41) | GAAL3MBTL1RAB9ANPC1MAPT | |
| SCHEMBL11935894 | 1.00 | GAA (0.41) | GAAL3MBTL1RAB9ANPC1MAPT | |
| SCHEMBL13564992 | 0.87 | MAPT (0.44) | GAAL3MBTL1RAB9ANPC1MAPT | |
| SCHEMBL17090550 | 0.87 | MAPT (0.44) | GAAL3MBTL1RAB9ANPC1MAPT | |
| SCHEMBL17090480 | 0.87 | MAPT (0.44) | GAAL3MBTL1RAB9ANPC1MAPT | |
| SCHEMBL13105770 | 0.87 | MAPT (0.44) | GAAL3MBTL1RAB9ANPC1MAPT | |
| SCHEMBL11935323 | 0.84 | GAA (0.45) | GAAL3MBTL1RAB9ANPC1MAPT | |
| SCHEMBL13565598 | 0.84 | GAA (0.44) | GAAL3MBTL1RAB9ANPC1MAPT | |
| SCHEMBL13565654 | 0.84 | GAA (0.44) | GAAL3MBTL1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |