Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564888 | 1.00 | NPY5R (0.43) | NPY5RGRIA2CNR1CNR2BRD4 | |
| SCHEMBL13565620 | 0.88 | CNR1 (0.36) | NPY5RCNR1CNR2 | |
| SCHEMBL17090175 | 0.88 | CNR1 (0.36) | NPY5RCNR1CNR2 | |
| SCHEMBL13565905 | 0.88 | NPY5R (0.37) | NPY5R | |
| SCHEMBL17090240 | 0.88 | NPY5R (0.37) | NPY5R | |
| SCHEMBL17090396 | 0.86 | NPY5R (0.36) | NPY5R | |
| SCHEMBL13565928 | 0.86 | NPY5R (0.36) | NPY5R | |
| SCHEMBL17090158 | 0.85 | NPY5R (0.35) | NPY5RBRD4 | |
| SCHEMBL13565437 | 0.85 | NPY5R (0.35) | NPY5RBRD4 | |
| SCHEMBL13564881 | 0.85 | LRRK2 (0.37) | NPY5RGRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |