Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565111 | 1.00 | MAPT (0.40) | MAPTKDM4EGAAALOX15ALOX12 | |
| SCHEMBL11935309 | 0.87 | MAPT (0.46) | MAPTKDM4EGAAALOX15ALOX12 | |
| SCHEMBL11941262 | 0.87 | MAPT (0.46) | MAPTKDM4EGAAALOX15ALOX12 | |
| SCHEMBL17090289 | 0.87 | MAPT (0.46) | MAPTKDM4EGAAALOX15ALOX12 | |
| SCHEMBL13565349 | 0.86 | MAPT (0.40) | MAPTKDM4EGAAALOX15ALOX12 | |
| SCHEMBL13565508 | 0.86 | MAPT (0.37) | MAPTKDM4EGAAALOX15ALOX12 | |
| SCHEMBL13565361 | 0.86 | MAPT (0.37) | MAPTKDM4EGAAALOX15ALOX12 | |
| SCHEMBL17090283 | 0.86 | MAPT (0.40) | MAPTKDM4EGAAALOX15ALOX12 | |
| SCHEMBL11936099 | 0.83 | L3MBTL1 (0.36) | MAPTKDM4EGAAALOX15ALOX12 | |
| SCHEMBL11941265 | 0.83 | L3MBTL1 (0.36) | MAPTKDM4EGAAALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |