Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.60 |
| ▸ | NPY1R | P25929 | 3/20 | 0.59 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564858 | 1.00 | NPY5R (0.60) | NPY5RNPY1RACACBCXCR4TPSAB1 | |
| SCHEMBL13564823 | 0.84 | NPY5R (0.60) | NPY5RNPY1RCXCR4TPSAB1CA12 | |
| SCHEMBL10113306 | 0.83 | ALDH1A1 (0.47) | NPY5R | |
| SCHEMBL13203840 | 0.83 | ALDH1A1 (0.47) | NPY5R | |
| SCHEMBL13564875 | 0.80 | NPY5R (0.56) | NPY5RNPY1RACACBHDAC1HDAC2 | |
| SCHEMBL17090344 | 0.80 | NPY5R (0.56) | NPY5RNPY1RACACBHDAC1HDAC2 | |
| SCHEMBL13565577 | 0.80 | NR1H4 (0.46) | NPY5RNPY1RCA1CA2 | |
| SCHEMBL17090300 | 0.80 | NPY5R (0.59) | NPY5RNPY1RCA12CA1CA2 | |
| SCHEMBL13565399 | 0.80 | NPY5R (0.59) | NPY5RNPY1RCA12CA1CA2 | |
| SCHEMBL13565094 | 0.79 | NPY5R (0.50) | NPY5RNPY1RHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |