Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565771 | 1.00 | CNR2 (0.49) | CNR2POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17090310 | 0.93 | MAPT (0.45) | CNR2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL13564932 | 0.93 | MAPT (0.45) | CNR2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11935135 | 0.84 | CNR2 (0.44) | CNR2POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17090246 | 0.84 | CNR2 (0.44) | CNR2POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11936288 | 0.83 | DRD2 (0.38) | CNR2BACE1BACE2NPY5R | |
| SCHEMBL13462747 | 0.83 | CNR2 (0.37) | CNR2ALDH1A1BACE1BACE2NPY5R | |
| SCHEMBL13438765 | 0.83 | CNR2 (0.37) | CNR2ALDH1A1BACE1BACE2NPY5R | |
| SCHEMBL17090262 | 0.81 | CNR2 (0.42) | CNR2POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13565934 | 0.81 | CNR2 (0.42) | CNR2POLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |