Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.41 |
| ▸ | NPY1R | P25929 | 4/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564876 | 1.00 | NPY5R (0.41) | NPY5RNPY1RSSTR1SSTR4ACHE | |
| SCHEMBL13565071 | 0.85 | NPY5R (0.42) | NPY5RNPY1RACHE | |
| SCHEMBL13203843 | 0.84 | NPY5R (0.47) | NPY5RSSTR1SSTR4ADORA2AADORA1 | |
| SCHEMBL10113307 | 0.84 | NPY5R (0.47) | NPY5RSSTR1SSTR4ADORA2AADORA1 | |
| SCHEMBL13565399 | 0.83 | NPY5R (0.59) | NPY5RNPY1RSSTR4 | |
| SCHEMBL17090300 | 0.83 | NPY5R (0.59) | NPY5RNPY1RSSTR4 | |
| SCHEMBL17090333 | 0.82 | NPY5R (0.57) | NPY5RNPY1RSSTR4DRD2 | |
| SCHEMBL13564872 | 0.82 | NPY5R (0.57) | NPY5RNPY1RSSTR4DRD2 | |
| SCHEMBL11934877 | 0.77 | ACHE (0.41) | NPY5RNPY1RACHEADORA2AADORA1 | |
| SCHEMBL13438738 | 0.77 | ACHE (0.41) | NPY5RNPY1RACHEADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |