Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565319 | 1.00 | CA2 (0.39) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL13439010 | 0.85 | CA2 (0.40) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL11935329 | 0.85 | CA2 (0.40) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL10114910 | 0.80 | SMN1; SMN2 (0.45) | HTTMEN1KMT2ANPC1S1PR2 | |
| SCHEMBL14424381 | 0.80 | SMN1; SMN2 (0.45) | HTTMEN1KMT2ANPC1S1PR2 | |
| SCHEMBL11935146 | 0.78 | GRIA2 (0.42) | CA2GRIA2MEN1KMT2ARAB9A | |
| SCHEMBL17090418 | 0.78 | GRIA2 (0.42) | CA2GRIA2MEN1KMT2ARAB9A | |
| SCHEMBL17090521 | 0.78 | CA2 (0.41) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL11935481 | 0.75 | CA2 (0.42) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL13439213 | 0.75 | CA2 (0.42) | CA2CA1CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |