Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565823 | 0.85 | PTGER4 (0.37) | KDM4EPTGER4KMT2ANPY5R | |
| SCHEMBL13203779 | 0.82 | NPY5R (0.46) | KDM4EKMT2AMEN1NPY5RALDH1A1 | |
| SCHEMBL10133363 | 0.82 | NPY5R (0.46) | KDM4EKMT2AMEN1NPY5RALDH1A1 | |
| SCHEMBL13438695 | 0.80 | PTGER4 (0.45) | KDM4EPTGER4KMT2AMEN1ALDH1A1 | |
| SCHEMBL11934825 | 0.80 | PTGER4 (0.45) | KDM4EPTGER4KMT2AMEN1ALDH1A1 | |
| SCHEMBL13565687 | 0.74 | NPY5R (0.31) | NPY5R | |
| SCHEMBL17090330 | 0.73 | KDM4E (0.41) | KDM4EKMT2AMEN1NPY5RALDH1A1 | |
| SCHEMBL13438912 | 0.71 | ACHE (0.46) | NPY5RALDH1A1CNR2MAPT | |
| SCHEMBL11935226 | 0.71 | ACHE (0.46) | NPY5RALDH1A1CNR2MAPT | |
| SCHEMBL17090185 | 0.70 | CNR2 (0.38) | PTGER4KMT2ANPY5RALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |