Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565984 | 0.88 | CA1 (0.59) | LMNAKDM4EALDH1A1HPGDHTT | |
| SCHEMBL13565235 | 0.88 | HPGD (0.54) | LMNAKDM4EALDH1A1HPGDHTT | |
| SCHEMBL13566019 | 0.88 | CA1 (0.50) | HTTMEN1KMT2ACA12CA1 | |
| SCHEMBL13565364 | 0.86 | KDM4E (0.50) | LMNAKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL13565241 | 0.86 | MEN1 (0.53) | LMNASMN1; SMN2MEN1KMT2ACA12 | |
| SCHEMBL13565065 | 0.86 | KDM4E (0.44) | LMNAKDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL13105811 | 0.85 | CA2 (0.42) | LMNAALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL11936062 | 0.84 | CA1 (0.62) | LMNAKDM4EALDH1A1HTTMEN1 | |
| SCHEMBL13566058 | 0.84 | CA1 (0.45) | ADRB2ADRB1ADRB3TRPV1CA12 | |
| SCHEMBL13566065 | 0.84 | FFAR1 (0.55) | ALDH1A1HTTMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |