Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564957 | 1.00 | NPY5R (0.42) | NPY5RPI4KBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17090195 | 0.89 | CA2 (0.41) | PI4KBMEN1KMT2ASMN1; SMN2ACHE | |
| SCHEMBL13565170 | 0.89 | CA2 (0.41) | PI4KBMEN1KMT2ASMN1; SMN2ACHE | |
| SCHEMBL17090418 | 0.85 | GRIA2 (0.42) | NPY5RPI4KBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11935146 | 0.85 | GRIA2 (0.42) | NPY5RPI4KBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10113384 | 0.81 | CSNK2A2 (0.54) | NPY5RMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL13203876 | 0.81 | CSNK2A2 (0.54) | NPY5RMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL13565081 | 0.80 | CNR2 (0.39) | NPY5RJAK2 | |
| SCHEMBL17089941 | 0.80 | CNR2 (0.39) | NPY5RJAK2 | |
| SCHEMBL11935329 | 0.79 | CA2 (0.40) | NPY5RPI4KBMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |