Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565137 | 1.00 | GRIA2 (0.33) | GRIA2BRD4NPY5RVCPGLO1 | |
| SCHEMBL17090187 | 0.84 | GRIA2 (0.35) | GRIA2BRD4 | |
| SCHEMBL13564938 | 0.83 | GRIA2 (0.38) | GRIA2BRD4VCP | |
| SCHEMBL17090037 | 0.83 | GRIA2 (0.38) | GRIA2BRD4VCP | |
| SCHEMBL13204429 | 0.81 | ADORA2A (0.41) | GRIA2ALDH1A1POLBKDM4EMAPT | |
| SCHEMBL10114931 | 0.81 | ADORA2A (0.41) | GRIA2ALDH1A1POLBKDM4EMAPT | |
| SCHEMBL13439241 | 0.80 | PTGER4 (0.37) | VCPPTGER4 | |
| SCHEMBL11935505 | 0.80 | PTGER4 (0.37) | VCPPTGER4 | |
| SCHEMBL13565968 | 0.79 | TAAR1 (0.40) | GRIA2NPY5RVCP | |
| SCHEMBL17090371 | 0.79 | TAAR1 (0.40) | GRIA2NPY5RVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |