Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 6/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090540 | 0.84 | GRIA2 (0.33) | GRIA2BRD4 | |
| SCHEMBL13565137 | 0.84 | GRIA2 (0.33) | GRIA2BRD4 | |
| SCHEMBL12882332 | 0.82 | ADORA2B (0.43) | GRIA2AAK1CYP1A2 | |
| SCHEMBL13565171 | 0.80 | AAK1 (0.41) | GRIA2AAK1CYP1A2 | |
| SCHEMBL17090257 | 0.74 | LIPC (0.40) | GRIA2BRD4 | |
| SCHEMBL13564891 | 0.74 | LIPC (0.40) | GRIA2BRD4 | |
| SCHEMBL13565174 | 0.74 | PTGER4 (0.36) | GRIA2BRD4 | |
| SCHEMBL17090197 | 0.74 | PTGER4 (0.36) | GRIA2BRD4 | |
| SCHEMBL13439494 | 0.73 | AAK1 (0.38) | AAK1 | |
| SCHEMBL17090158 | 0.73 | NPY5R (0.35) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |